Prenatal exposure to polycyclic aromatic hydrocarbons and effects on neonatal anthropometric indices and thyroid-stimulating hormone in a Middle Eastern population

Prenatal exposure to polycyclic aromatic hydrocarbons (PAHs) evokes extensive concerns regarding public health. Monitoring the pregnant women's can be considered a suitable alternative assess fetus's exposure. This study aimed monitor (n = 126) PAHs using biomonitoring approach evaluate effects on anthropometric indices and neonatal thyroid-stimulating hormone (TSH) in Shiraz, Iran. priority compounds were measured by gas chromatography-mass spectrometry (GC-MS) after separating blood serum liquid-liquid extraction (LLE) method. Information indices, TSH levels, data from respondents was obtained medical records questionnaires. The mean concentrations ranged 0.29 327.91 ng/g lipid. There no significant difference between maternal at seventh month pregnancy termination except for ACY (p-Value<0.05). Regression analysis results showed correlation (p-value<0.05) passive smoke total concentrations. relationship weight, height, head circumference, Apgar score of newborns. decreased 0.99 units as ACE increased per unit (β -0.001). is first relationships prenatal newborn health indicators, including levels Middle Eastern population. Future studies are suggested perform detailed assessments intake sources, especially vulnerable populations such women children.